Creatine has been updated, with three major focuses of the update.
Neurology and the intellectual implications of creatine were focused on. The point that creatine is vital to cognitive function driven, and the pharmacokinetics and production/absorption of creatine into the brain added to the pharmacology section.
Depression was added, with creatine seeming to be anti-depressive in women (but more evidence needed) and benefits occurring to both the serotonergic and dopaminergic systems. The cause is not known, but may be related to creatine just enhancing the function of all cells (enhanced membrane function, ATP buffering to protect from cell death)
Cyclocreatine was added, and is an interesting research molecule. It is a creatine mimetic not currently available for sale, and seems to passively diffuse through barriers and may benefit non-responders as well as those with genetic creatine transporter deficiencies.
General Layout and Maintenace of the page was conducted. Sections were merged, relocated, and added to enhance readability of the page. A lot more blue quote summaries
Were added to try and make the page more readable, and some minor corrections were made (some insufficient information was in the pharmacology section, and was corrected). Some wording was also changed to enhance how easy the page is to read.
Enjoy the update and share it if possible! We are confident there is no better page on Creatine any where else.